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目的：介绍一个理想的动物离体灌流肺模型，评价肺血管各部位的压力及血管抵抗纵向分布比率。方法：利用兔离体灌流肺模型，采用肺血流阻断法进行测定。结果：测定值分别为肺动脉压力：２０８６±１８２ ｋ Ｐａ；肺静脉压力：９８７±０６１ ｋ Ｐａ；毛细血管动脉侧压力：１６６３±１０４ ｋ Ｐａ；毛细血管压力：１４３５±１２０ ｋ Ｐａ；毛细血管静脉侧压力：１２１６±１２３ ｋ Ｐａ。通过大动脉、小动脉、小静脉、大静脉各段的抵抗分配比率分别为：３８％ 、２１％ 、２０％ 、２１％ 。结论：这种评价肺血管压力及抵抗分配的方法具有操作简便、测定时间短、定位准确的优点，是一种新型的实验方法。
OBJECTIVE: To introduce an ideal animal model of isolated perfused lung to evaluate the pressure and the longitudinal distribution of vascular resistance in various parts of the pulmonary blood vessels. Methods: Perfused lungs were isolated from rabbits by pulmonary perfusion. Results: The measured values were pulmonary arterial pressure: 20.86 ± 1.82 kPa; pulmonary vein pressure: 987 ± 061 kPa; capillary arterial pressure: 1663 ± 104 kPa; capillary Pressure: 14 35 ± 1 20 k Pa; capillary venous side pressure: 12 16 ± 1 23 k Pa. The distribution ratios of resistance across the aorta, arterioles, venules and venules were 38%, 21%, 20% and 21%, respectively. Conclusion: This method of evaluating pulmonary vascular pressure and resistance distribution has the advantages of simple operation, short determination time and accurate positioning. It is a new experimental method.