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白色念珠菌对三唑类抗真菌药物出现耐药性,是HIV感染病人发生难治性粘膜念珠菌病的一个重要原因。了解真菌对唑类抗真菌药物的耐药机制,对于预防或逆转这一过程的分子和生化过程是至关重要的。最近的研究表明,白色念珠菌对氟康唑产生耐药性的一个重要机制为抑制对氟康唑的摄取?
Candida albicans on triazole antifungal drug resistance, is an HIV infection in patients with refractory mucosal candidiasis is an important reason. Understanding the mechanisms of fungal resistance to azole antifungal agents is crucial to preventing or reversing the molecular and biochemical processes involved in this process. Recent studies have shown that Candida albicans fluconazole resistance is an important mechanism to inhibit the uptake of fluconazole?