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目的研究阿奇霉素联合双唑泰栓治疗宫颈支原体感染的临床效果。方法回顾性分析支原体感染患者150例,分为常规组(阿奇霉素)和研究组(阿奇霉素+双唑泰栓)各75例,比较2组临床疗效及不良反应情况。结果研究组治愈率57.3%、总有效率94.7%明显高于对照组(P<0.05),无效率5.3%显著低于对照组(P<0.01)。支原体培养转阴率81.3%显著高于常规组的29.3%(P<0.01),2组在用药不良反应上无差异。结论素联合双唑泰栓疗宫颈支原体感染抑菌效果显著,不良反应少且程度较轻,见效快,操作简单,经济适用。
Objective To study the clinical efficacy of azithromycin combined with metronidazole in treatment of cervical mycoplasma infection. Methods A retrospective analysis of 150 patients with mycoplasma infection was divided into routine group (azithromycin) and the study group (azithromycin + metronidazole methotrexate) in 75 cases, the clinical efficacy and adverse reactions were compared between the two groups. Results The cure rate of the study group was 57.3%, the total effective rate was 94.7%, significantly higher than that of the control group (P <0.05), and the inefficiency rate of 5.3% was significantly lower than that of the control group (P <0.01). Mycoplasma negative conversion rate of 81.3% was significantly higher than the conventional group 29.3% (P <0.01), two groups in the adverse drug reactions no difference. Conclusion The combined antibacterials and antibacterials of Mycoplasma hominis are effective in inhibiting the mycoplasma infection of cervix. Mycoplasma is more effective and less toxic.