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目的:探讨超纯水对于维持性血液透析患者的全身状况及生活质量的影响。方法:选取2012年5月-2013年5月常山县人民医院收治的维持性血液透析患者80例,采用重复测量自身对照的方法,检测使用超纯水前、后8个月患者血红蛋白(Hb)、红细胞压积(HCT)、血清白蛋白(ALB)、干体重及C-反应蛋白(CRP)、促红细胞生成素(EPO)用量等指标的变化。结果:与使用超纯水前比较,使用超纯水8个月后患者Hb、HCT、ALB水平及干体重均显著升高,差异具有统计学意义(P<0.05);与使用超纯水前比较,使用超纯水8个月后患者CRP水平及EPO使用剂量均显著降低,差异均具有统计学意义(P<0.05)。结论:使用超纯水能够显著改善维持性血液透析患者的贫血及营养状况,且能够显著降低患者炎症水平,减少患者费用支出。
Objective: To investigate the effect of ultrapure water on the general condition and quality of life in maintenance hemodialysis patients. Methods: Eighty patients with maintenance hemodialysis who were treated in Changshan County People’s Hospital from May 2012 to May 2013 were enrolled in this study. Hb was measured at 8 months before and 8 months after using ultrapure water by repeated measures of self-control. (HCT), serum albumin (ALB), dry weight, C-reactive protein (CRP), erythropoietin (EPO) Results: The levels of Hb, HCT, ALB and dry weight in patients with ultrapure water after 8 months of treatment were significantly higher than those before using ultrapure water. The difference was statistically significant (P <0.05) Compared with 8 months after using ultrapure water, patients’ CRP level and EPO dosage were significantly lower (P <0.05). Conclusion: The use of ultrapure water can significantly improve anemia and nutritional status of maintenance hemodialysis patients, and can significantly reduce the level of inflammation in patients and reduce patient costs.