【摘 要】
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In order to understand the molecules mechanism of ion irradiation,which has been widelyused in many fields such as cancer therapy, uracil, one of the bases ofnu
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In order to understand the molecules mechanism of ion irradiation,which has been widelyused in many fields such as cancer therapy, uracil, one of the bases ofnucleic acid,waschosen in the low energy ion radiolysis research. The solid uracil films with mass thickness of0.314 mg/cm2 were irradiated by 200 keV H+ ions.The experimental results show that 200 keVH+ ions are effective in decomposition of uracil molecules. One of the decomposition products,5,6-dihydro-uracil, was separated by high performance liquid chromatograph (HPLC) anddetected using an UV-light detector. Its yield increases first but then decreases as the ion doseincreasing. In addition, the mechanism of uracil decomposition and 5,6-dihydro-uracilformation was also discussed.
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