目的：生长抑素作为一种新的人工合成的肽类激素，在临床的应用越来越广泛，为此，对其药理作用及临床应用作了简述。方法：查阅近年来国内外有关文献资料进行整理归纳。结果：生长抑素能抑制体内多种激素的释放，临床上用于治疗食管静脉曲张破裂出血、非食管静脉曲张的消化道出血、预防或治疗急性胰腺炎、防止术后腹瘘形成和促使胶瘘愈合、抑制Ｏｄｄｉ括约肌运动等方面具有良好的作用。结论：该药具有起效快，易使用，且安全无毒副作用，在抢救和治疗消化道出血、出血坏死性胰腺炎等疾病中都具有重要意义 OBJECTIVE: Somatostatin, as a new synthetic peptide hormone, has become more and more widely used in clinic. To this end, its pharmacological effects and clinical application are briefly described. Methods: Consult the literature data at home and abroad in recent years for collation. Results: Somatostatin can inhibit the release of a variety of hormones in the body, clinically used for the treatment of esophageal variceal bleeding, non-esophageal varices gastrointestinal bleeding, prevention or treatment of acute pancreatitis, prevention of postoperative fistula formation and to promote glue Fistula healing, inhibition of Oddi sphincter movement and so has a good effect. Conclusion: The drug has fast onset, easy to use, safe and non-toxic side effects, in the rescue and treatment of gastrointestinal bleeding, hemorrhagic necrotizing pancreatitis and other diseases are of great significance