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目的:分析某院夜间急诊的抗生素使用情况,旨在为安全、有效、合理地使用抗生素提供理论依据。方法:选取2012年6月26日—2012年7月25日某院夜间急诊处方2924张作为研究对象,对抗生素的使用率、使用药物的种类、联合用药情况及应用抗生素不合理等情况进行分类统计,并将所得数据进行回顾性的分析。结果:在我们调查抽取的2924张夜间急诊处方中,使用抗生素的处方有510张,抗生素使用率为17.44%(在使用抗生素的处方中,大多数处方系用于治疗呼吸道感染性疾病),其中单纯应用抗生素的处方占抗生素处方总数的79.08%,二联用药的处方占抗生素处方总数的20.92%,三联用药的处方占抗生素处方总数的0%,与中药注射剂联合应用的处方占抗生素处方总数的13.73%,将注射抗生素与口服抗生素联合应用的处方占抗生素处方总数的37.35%,应用抗生素不合理的处方占抗生素处方总数的6.54%。结论:本次调查结果显示,某院夜间急诊的抗生素使用情况基本合理,但仍存在一些问题。医务人员在使用抗菌药物时一定要严格遵守《抗菌药物临床应用指导原则》,首选敏感、窄谱及价廉的抗菌药物,并注意所选药物或联合用药的合理性及用药剂量,规范用药疗程。
OBJECTIVE: To analyze the use of antibiotics at a night emergency clinic in a hospital and to provide a theoretical basis for the safe, effective and rational use of antibiotics. Methods: From June 26, 2012 to July 25, 2012, 2924 nocturnal emergency prescriptions in a hospital were selected as research objects to classify antibiotics usage rate, types of drugs used, combination therapy and irrational use of antibiotics Statistics, and the resulting data for a retrospective analysis. Results: Of the 2,924 night-time emergency prescriptions drawn from our survey, there were 510 prescriptions for antibiotics and an antibiotic use rate of 17.44% (most of the prescriptions for antibiotics were used to treat respiratory infections), of which The prescriptions for antibiotics alone accounted for 79.08% of the total number of antibiotics, 20.52% of prescriptions for antibiotics and 0.9% for prescriptions of triple antibiotics. The prescriptions for combination with traditional Chinese injections accounted for the total number of prescriptions for antibiotics 13.73%. The combination of antibiotic injection and oral antibiotics accounted for 37.35% of the total number of prescription antibiotics. The unreasonable use of antibiotics accounted for 6.54% of the total number of prescription antibiotics. Conclusion: The findings of this survey show that the use of antibiotics at night emergency clinics in a hospital is basically reasonable, but there are still some problems. Medical staff in the use of antimicrobial drugs must strictly abide by the “Guidelines for the clinical application of antimicrobial agents,” the preferred sensitivity, narrow spectrum and inexpensive antibiotics, and pay attention to the rationality of drug or combination of drugs and dosage, the standard drug treatment .