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神经肽W(NPW)是2002年被发现的下丘脑神经肽,为G蛋白偶联受体GPR7和GPR8的内源性配体.NPW受体存在于中枢神经系统及外周组织器官,认为可能作为神经递质或调质参与多种生理功能的调节.NPW受体的药理学作用及生理学特性已引起诸多学者关注.本研究就NPW对能量的稳态、应激和疼痛的影响研究进展进行了综述.1 NPW的生物学特性NPW是新型下丘脑神经肽~([1]),首次从猪的下丘
Neuropeptide W (NPW) is a hypothalamic neuropeptide that was discovered in 2002. It is an endogenous ligand of G protein-coupled receptors GPR7 and GPR 8. NPW receptors are found in the central nervous system and peripheral tissues and organs and are thought to act as Neurotransmitters or temmints are involved in the regulation of various physiological functions.Now pharmacological and physiological properties of NPW receptors have attracted the attention of many scholars.In this study, NPW on energy homeostasis, stress and pain were studied Summary 1. Biological characteristics of NPW NPW is a novel hypothalamic neuropeptide ~ ([1]), for the first time from the pig’s inferior colliculus