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原发性肝癌是世界上10种发病率最高的恶性肿瘤之一,在我国居第2位,其恶性程度很高,极易发生浸润转移,手术疗效较差,即使是小肝癌(<5cm)行根治切除或行肝脏移植后,3年复发率也高达50%以上。本文就与肝癌浸润转移有关的病理特征以及相关的分子因素作一简要综述,旨在为临床上判断肝癌的预后并改善其疗效提供线索。一、肝癌的大小及分化程度
Primary liver cancer is one of the 10 most common malignancies in the world. It ranks second in China. It is highly malignant and can easily undergo infiltration and metastasis. The curative effect is poor, even small hepatocellular carcinoma (<5cm). After radical resection or liver transplantation, the recurrence rate is as high as 50% for 3 years. This article briefly reviewed the pathological features and related molecular factors related to the invasion and metastasis of hepatocellular carcinoma, aiming to provide clinical clues for judging the prognosis of liver cancer and improving its efficacy. First, the size and differentiation of liver cancer