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本文阐述了细胞间隙连接通讯的生理功能及其异常与癌症的发生、化学物质的毒作用机制以及细胞凋亡的关系，并对调节细胞间隙连接通讯的毒理学意义进行了讨论。
This article describes the physiological functions of gap junctional intercellular communication and its abnormalities and the occurrence of cancer, the mechanism of chemical toxicity and apoptosis, as well as the toxicological significance of regulating the gap junctional intercellular communication.