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[目的]制定代谢综合征诊断指标的多元医学参考值。[方法]随机抽取2008年6～12月在汕头大学附属第一医院慢性病监测点的潮汕居民为研究对象,检测空腹血糖、甘油三酯、脂蛋白及现场测量身高、体重、血压、腰围等指标,获取124例代谢综合征患者及400例健康者的资料,运用三类指标组合指标法确定代谢综合征诊断指标的95%多元医学参考值,并采用多指标ROC分析法对其诊断价值进行评价。[结果]分别得出男女代谢综合征95%多指标医学参考值,且利用多元参考值诊断的多指标ROC曲线面积男性为(0.9372±0.0180),灵敏度=0.8462,特异度=0.9700;女性为(0.9652±0.0174),灵敏度=0.9394,特异度=0.9650,男性和女性多指标ROC曲线面积AUC95%可信区间均不包括0.5。[结论]三类指标组合指标法制定的95%多指标医学参考值在诊断监测人群代谢综合征时具有较高的参考价值。
[Objective] To develop multiple medical reference values for the diagnosis of metabolic syndrome. [Methods] The residents of Chaoshan residents at the chronic disease monitoring station of the First Affiliated Hospital of Shantou University from June 2008 to December 2008 were selected randomly to detect fasting blood glucose, triglycerides, lipoproteins and measure the height, weight, blood pressure, waist circumference and other indicators The data of 124 patients with metabolic syndrome and 400 healthy controls were obtained. The 95% multiple medical reference value for the diagnosis of metabolic syndrome was determined by the combination of three indexes, and the diagnostic value was evaluated by multi-index ROC analysis . [Results] The 95% multi-index medical reference values of men and women metabolic syndrome were respectively obtained. The multi-index ROC curve area (m = 0.9372 ± 0.0180), sensitivity = 0.8462 and specificity = 0.9700 0.9652 ± 0.0174), sensitivity = 0.9394, and specificity = 0.9650. The multiple target ROC curve areas for male and female AUC95% confidence intervals do not include 0.5. [Conclusion] The 95% multi-index medical reference value established by the three index combination index method has high reference value in the diagnosis and monitoring of metabolic syndrome.