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作者用旋毛虫幼虫感染小鼠,每鼠约200条。实验分5组,第1组于感染后24小时给予 Avermectin B_2a0. 3毫克/公斤,一次口服。第2组在服药前1小时腹膜内注射阿托品3毫克/公斤。其余3组分别为只给阿托品组、溶解药物的溶剂组和不作任何处理的对照组。各组均于感染后3天剖检肠内虫数。结果服药组减虫率分别为85％和71％,两组无显著差异。后3组虫数均十分接近。
The authors infected mice with Trichinella larvae, about 200 mice. The experiment was divided into 5 groups, the first group was given 24 hours after infection Avermectin B_2a0.3 mg / kg, once orally. Group 2 received an intraperitoneal injection of atropine 3 mg / kg 1 hour before taking the drug. The remaining three groups were only given atropine group, dissolved drug solvent group and without any treatment control group. All groups were killed 3 days after infection in the number of intestinal insects. Results The worm reduction rates in the medication group were 85% and 71%, respectively, with no significant difference between the two groups. After 3 groups of worms are very close.