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目的探讨中西药结合综合治疗慢性肾功能衰竭氮质血症期,以稳定和延缓病程进展。方法将46例符合慢性肾功能衰竭(CRF)诊断标准的病人随机分为治疗组和对照组,两组均常规予低蛋白、低磷饮食,抗高血压、控制感染、纠酸等药物治疗,治疗组另加补消合用的中药汤剂煎服,日一次,1个月为一个疗程。结果治疗组总有效率82.5%,对照组总有效率52.2%,两组比较有显著性差异(P<0.05)。两组治疗前后检测肾功能及症状、体征,经统计分析,治疗组治疗后血尿素氮(BUN)、血肌酐(Scr)与治疗前相比有显著性差异(P<0.05、P<0.01),与对照组比较有统计学意义(P<0.01、P<0.05)。在改善各症状方面,也有显著性差异(P<0.05)。结论中西医结合综合治疗慢性肾功衰竭氮质血症期,可改善肾功能及缓解减轻症状,疗效满意,对稳定和缓解肾功能进展起积极的作用。
Objective To explore the combination of traditional Chinese and western medicine in the treatment of azotemia in chronic renal failure in order to stabilize and delay the progression of the disease. Methods 46 cases of patients with CRF were randomly divided into treatment group and control group. Both groups were routinely given low-protein and low-phosphorus diet, antihypertensive, infection control and acid-correcting medication, The treatment group plus complement Chinese herbal decoction, once a day, a month for a course of treatment. Results The total effective rate was 82.5% in the treatment group and 52.2% in the control group, with significant difference between the two groups (P <0.05). The renal function, symptoms and signs before and after treatment were detected in both groups. After statistical analysis, the blood urea nitrogen (BUN) and serum creatinine (Scr) in the treatment group were significantly different from those before treatment (P <0.05, P <0.01) , Compared with the control group was statistically significant (P <0.01, P <0.05). There were also significant differences in improving symptoms (P <0.05). Conclusion The integrated traditional Chinese and western medicine treatment of azotemia in chronic renal failure can improve renal function and relieve symptoms. The curative effect is satisfactory and plays a positive role in stabilizing and relieving the progression of renal function.