一氧化氮（NO）是一种高反应的自由基气体，它参与神经传导、免疫反应、血小板凝集和血压控制[1]。近10a来受到国内外学者关注。本文观察了18例肾病综合征患儿尿NO代谢产物亚硝酸盐（NO2）／硝酸盐（NO3）及环磷酸鸟苷（cGMP）的变化。材料与方法一、对象：本文观察1997年1月～ Nitric oxide (NO) is a highly reactive free radical gas that is involved in nerve conduction, immune responses, platelet aggregation and blood pressure control [1]. Nearly 10 years to be domestic and foreign scholars attention. In this paper, the changes of urinary NO metabolites nitrite (NO3) and nitrate (NO3) and cyclic guanosine monophosphate (cGMP) in 18 children with nephrotic syndrome were observed. Materials and methods First, the object: This article observed in January 1997 ~