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作者对1984年1月~1987年12月确诊的102例布氏杆菌病儿童患者进行了研究。诊断以临床征象和布氏杆菌凝集试验≥1:160及/或血培养和组织培养阳性为依据。研究对象年龄≤14岁,且均为首次感染。每例均详细询问病史并全面查体。实验室查血细胞计数、血沉、肝肾功能、布氏凝集试验、肥达氏反应,并作血培养及尿液分析。根据患者的年龄、病情轻重、对药物的耐受性、血培养结果和药敏试验选择抗生素:复方新诺明(TMP-SMX)每日10/50mg/kg,分2次口服;四环素每日40mg/kg,分4次
The authors studied 102 patients with brucellosis who were diagnosed between January 1984 and December 1987. Diagnosis is based on clinical signs and brucellosis agglutination test ≥1: 160 and / or positive blood and tissue culture. The subjects were ≤14 years of age and were all first-time infected. Each case were asked in detail about the history and a comprehensive examination. Laboratory check blood cell count, ESR, liver and kidney function, Brinell agglutination test, Widal reaction, and for blood culture and urine analysis. Antibiotics were selected according to the patient’s age, severity of illness, drug resistance, blood culture results, and susceptibility testing: TMP-SMX 10/50 mg / kg orally twice daily; tetracycline daily 40mg / kg, 4 times