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目的探讨银杏叶提取物片对鼻咽癌放疗患者听力受损的影响。方法选择我院2013年12月~2016年12月收治的鼻咽癌放疗患者60例,随机分为观察组和对照组,每组30例。两组均给予鼻咽癌放疗,观察组同时给予银杏叶提取物片治疗。两组患者均连续治疗3个月,观察两组放疗前后听力受损情况。结果观察组听力改善总有效率高于对照组,差异有统计学意义(P<0.05)。观察组放疗前气导听阈值、中耳压力(MEP)分别和对照组放疗前气导听阈值、MEP比较,差异无统计学意义(P>0.05);观察组放疗后气导听阈值低于对照组放疗后气导听阈值,观察组放疗后MEP高于对照组,差异有统计学意义(P<0.05)。结论银杏叶提取物片能够降低鼻咽癌放疗期间中内耳损伤程度,效果显著。
Objective To investigate the effect of Ginkgo biloba extract tablets on hearing loss of patients with nasopharyngeal carcinoma undergoing radiotherapy. Methods Sixty patients with nasopharyngeal carcinoma treated by radiotherapy from December 2013 to December 2016 in our hospital were randomly divided into observation group and control group, with 30 cases in each group. Both groups were given nasopharyngeal carcinoma radiotherapy, observation group also given gingko leaf extract tablets treatment. Two groups of patients were treated for 3 months, the two groups were observed before and after hearing loss. Results The total effective rate of hearing improvement in observation group was higher than that in control group, the difference was statistically significant (P <0.05). There was no significant difference between the two groups (P> 0.05). The threshold of air conduction before radiotherapy in the observation group was lower than that of the control group (P> 0.05) The control group after air-conduction hearing threshold, the observation group after radiotherapy MEP higher than the control group, the difference was statistically significant (P <0.05). Conclusion Ginkgo biloba extract tablets can reduce the extent of damage to the inner ear during radiotherapy of nasopharyngeal carcinoma, the effect is significant.