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目的:以早产儿、足月新生儿和幼儿为对象,研究其体内注射英脱利匹特后血液流变学的改变情况。现已知,英脱利匹特引起的循环系统并发症,如肺循环和体循环血流阻力增加,与血液流变学变化有关。方法:收集处于全胃肠外营养期的病例,分成早产儿组、足月儿组和幼儿组,每组均为10例,给予初始剂量的英脱利匹特后,间隔4 h再次输注(0.6 g/kg)。另外,采取10例健康早产儿、10例足月新生儿和10例成人的血液样本,用英脱利匹特进行试管培养。英脱利匹特输注前后,以及用英脱利匹特进行试管血液培养前后,分别检测全血黏度和血浆黏度(用毛细血管黏度计测定),红细胞(RBC)
OBJECTIVE: To study the changes of hemorrheology in preterm infants, full term newborns and young children after their in vivo injection of triprolidine. It is known that the effects of intralipit on circulatory system complications, such as increased resistance to pulmonary circulation and systemic blood flow, are associated with changes in blood rheology. Methods: The cases of total parenteral nutrition were collected and divided into premature infants, full-term infants and young infants, with 10 in each group. After the initial dose of Impalpit (0.6 g / kg). In addition, blood samples from 10 healthy preterm infants, 10 full-term newborns, and 10 adult adults were tested in IV culture with testosterone. Blood viscosity and plasma viscosity (measured by capillary viscometer), red blood cell (RBC)