慢性阻塞性肺疾病(简称慢阻肺)Ⅱ级患者多不伴有动脉血酸碱度的改变,如果诱发癫痫发作时可引发严重的酸中毒,导致严重后果。但是,报道的大多数均在糖尿病的基础上诱发酮症酸中毒较多,而单纯引发重度乳酸性酸中毒(LA)极少报道[1]。本例患者在慢阻肺的基础上,诱发了癫痫发作,继发重度LA,经合理治疗后痊愈。现结合文献资料,对慢阻肺诱发癫痫发作并重度LA诊治经验总结报告如下。临床资料患者64岁,男性。因“反复气喘、气短9年余,加重5 d”于2014年1月27日入院。查体:桶状胸,双肺叩诊过清音,语颤减弱,呼吸音对称性减低,可闻及少许干鸣音,无湿啰音。根据病史 Chronic obstructive pulmonary disease (referred to as chronic obstructive pulmonary) Ⅱ level patients are often not associated with changes in arterial pH, if induced seizures can cause severe acidosis, leading to serious consequences. However, most of the reports reported more ketoacidosis on the basis of diabetes, whereas mere reports of severe lactic acidosis (LA) were seldom reported [1]. This patient on the basis of chronic obstructive pulmonary disease, induced seizures, secondary severe LA, recovered after reasonable treatment. Now combined with literature, chronic obstructive pulmonary disease induced seizures and severe LA diagnosis and treatment experience summary report is as follows. Clinical data Patient 64 years old, male. Because of “repeated asthma, shortness of breath more than 9 years, increased 5 d ” was January 27, 2014 admission. Physical examination: barrel chest, lung percussion over the voiceless, tremor weakens, reduced symmetrical breath sounds, can be heard a little dry beep, no wet rales. According to medical history