我院1979～1988年精神障碍病人住院死亡20例,其中与抗精神剂治疗有关者11例;占病死数55%,报告如下。临床资料本组11例,其中女6例,男5例;年龄19～47岁,平均31.7岁。原发病为精神分裂症9例,散发性脑炎和抑郁症各1例。死亡原因:猝死5例,中暑、恶性综合征和心血管系并发症各2例。接受抗精神药物治疗前均无躯体疾患。无药瘾及药物过敏史。家族中无猝死及其他遗传病史。讨论一、猝死猝死系指直至死前24小时仍无死亡之迹象 In our hospital from 1979 to 1988 mental illness patients hospitalized in 20 cases, of which 11 cases were associated with antipsychotics; accounting for 55% of deaths, the report is as follows. Clinical data The group of 11 cases, of which 6 were women, 5 males; aged 19 to 47 years, mean 31.7 years. The primary disease was schizophrenia in 9 cases, sporadic encephalitis and depression in 1 case. Causes of death: sudden death in 5 cases, heat stroke, malignant syndrome and cardiovascular complications in 2 cases. There was no physical illness before receiving antipsychotic medication. No drug addiction and drug allergy history. No sudden death in the family and other genetic medical history. Discussion First, sudden death from sudden death means that there is still no sign of death until 24 hours before death