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探讨急性心肌梗死(AMI)溶栓前后QT离散度的变化与溶栓疗效的关系。测量40例AMI患者的QT间期,计算其QTd及校正后的QT离散度(QTcd)。结果溶栓再通组(23例)溶栓后小时QT离散度明显增加,以后逐渐缩短。溶栓来再通组(17例)溶栓后2小时、2天的QT离散度无明显变化,溶栓后7天～14天的QT离散度较治疗前缩短。溶栓再通组7天～14天的QT离散度较溶栓未再通组明显缩短,二者差异有显著性(P<0.01)。结论 QT离散度的动态变化与溶栓疗效有关,溶栓后QTd及QTcd缩短提示溶栓后血管再通。
To investigate the relationship between changes of QT dispersion before and after thrombolysis in acute myocardial infarction (AMI) and curative effect of thrombolysis. QT interval was measured in 40 patients with AMI, QTd and corrected QT dispersion (QTcd) were calculated. Results Thrombolytic reperfusion group (23 cases) QT dispersion significantly increased after hours, then gradually shortened. QT dispersion did not change significantly at 2 days after thrombolysis in thrombolytic group (17 cases), and QT dispersion at 7 days to 14 days after thrombolysis was shorter than that before treatment. The QT dispersion of thrombolytic recanalization group from 7 days to 14 days was significantly shorter than that of thrombolytic non-recanalization group, the difference was significant (P <0.01). Conclusions The dynamic change of QT dispersion is related to the effect of thrombolytic therapy. Shortening of QTd and QTcd after thrombolysis suggests recanalization of blood vessels after thrombolysis.