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用放射免疫法检测56例慢性肾炎肾衰患者,对比观察29例急性肾炎患者乙肝病毒标志。结果表明:慢性肾炎肾衰患者HBV感染率和抗-HBs阳性率显著高于急性肾炎及一般人群,HBsAg阳性率明显低于对照组。提示从急性肾炎向慢性肾炎肾衰发展过程中患者具有一定清除病毒的能力,随着抗-HBs产生,HBsAg和抗-HBs免疫复合物的形成有可能促进了肾损害的发生或加重了原有的损伤。
Fifty-six patients with chronic nephritis and renal failure were detected by radioimmunoassay, and hepatitis B virus markers were compared among 29 patients with acute nephritis. The results showed that the positive rates of HBV infection and anti-HBs in chronic nephritis patients with renal failure were significantly higher than those in acute nephritis and the general population. The positive rate of HBsAg was significantly lower than that of the control group. Prompted from the acute nephritis to chronic nephritis renal failure during the development of patients with a certain ability to clear the virus, with the anti-HBs production, HBsAg and anti-HBs immune complex formation may promote the occurrence of renal damage or aggravate the original Damage.