联产醋酸酐和醋酸酯的方法包括将醋酸在高温下产生第一烯酮流,烯酮流是气相流包括烯酮、乙酸和水;冷却第一烯酮流浓缩醋酸和水,从而产生(i)弱酸性水流和(ii)乙烯酮原料流;提供的乙烯酮原料流到醋酸乙烯酮反应器中,烯酮和乙酸反应生成乙酸酐;同时与步骤(c),其中产生的弱酸水流到乙酸酯化反应器中,弱酸流与醋酸合成有机醇酯。优选地,有机醇选自(i)形成乙酸酯,酯和任选的 A method of co-producing acetic anhydride and acetate includes generating acetic acid at a high temperature to produce a first enone stream, the enone stream being a gas phase stream comprising ketene, acetic acid, and water; cooling the first enone stream to concentrate the acetic acid and water to produce ( i) a weakly acidic water stream and (ii) a ketene feedstream; providing a ketene feedstream to an acetoacetate reactor, reacting the ketene and acetic acid to form acetic anhydride; and simultaneously with step (c) Acetic acid esterification reactor, weak acid and acetic acid synthesis of organic alcohol ester. Preferably, the organic alcohol is selected from (i) forming acetate, ester and optionally