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目的 :探讨多原发大肠癌 (MPCC)的预防、诊断和治疗。方法 :对该院于 1992～ 1999年收治的 1796例原发大肠癌患者中发现的 37例多原发大肠癌就其临床特点、诊断和治疗等情况进行回顾性临床研究。结果 :本组 37例MPCC共发现大肠癌肿 75处 ,占同期收治的原发大肠癌 2 .1% (37/ 1796 ) ,其中同时性癌 (SC) 0 .7%(13/ 1796 ) ,异时性癌 (MC) 1.4% (2 4/ 1796 )。 37例多原发大肠癌中 12例 (32 % )伴大肠腺瘤 ,其中 4例腺瘤癌变。 3例SC因远端肿瘤引起肠腔狭窄 ,采用气囊扩张后作结肠镜检查发现近端癌肿。本组总根治性切除率 84% (31/ 37)。结论 :为提高MPCC诊断率、减少漏诊 ,除对其高危人群进行定期全结肠镜检查和大肠腺瘤切除外 ,术前全结肠镜检查和术后的定期随访是非常重要的
Objective: To explore the prevention, diagnosis and treatment of multiple primary colorectal cancer (MPCC). Methods: A retrospective clinical study was conducted on the clinical features, diagnosis and treatment of 37 cases of multiple primary colorectal cancer in 1796 cases of primary colorectal cancer treated in our hospital from 1992 to 1999. Results: Totally 75 colorectal carcinomas were found in 37 cases of MPCC, accounting for 2. 1% (37/1796) of the primary colorectal cancers admitted in the same period, with 0.7% (13/1796) of simultaneous cancers (SC) Synchronous cancer (MC) 1.4% (24/1796). In 37 cases of multiple primary colorectal cancer, 12 cases (32%) had colorectal adenoma, of which 4 cases had adenocarcinoma. 3 cases of SC due to distal tumor caused by intestinal stricture, the use of balloon dilatation for colonoscopy found proximal cancer. The total radical resection rate of 84% (31/37). CONCLUSIONS: To improve the diagnostic rate of MPCC and reduce missed diagnosis, it is very important that colonoscopy and regular follow-up be performed in addition to regular colonoscopy and resection of colorectal adenomas in high-risk individuals