据统计,全世界约有1.76亿 HBsAg 携带者,其中大多数以往没有 HBV 感染的临床症象。这些携带者有可能发展成慢性 HBV感染后遗症的危险,如慢性活动性肝炎、肝硬变及原发性肝细胞癌(PHC)等。然而,以往对于无症状 HBsAg 携带者的长期血清学转归还不十分清楚。自1971年来,作者对由普查中确诊的150名 HBsAg 携带者进行了血清学随访。其目的在于了解无症状人群中携带 HBsAg的持久性;携带者的年龄与性别在 HBeAg According to statistics, there are about 176 million HBsAg carriers in the world, and most of them have no previous clinical signs of HBV infection. These carriers are likely to develop the risk of sequelae of chronic HBV infection, such as chronic active hepatitis, cirrhosis and primary hepatocellular carcinoma (PHC). However, the long-term serological outcome of asymptomatic HBsAg carriers is not well understood. Since 1971, the authors conducted a serological follow-up of 150 HBsAg carriers confirmed by the census. Its purpose is to understand the persistence of HBsAg in asymptomatic populations; the age and sex of the carrier are among HBeAg