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为给我省将风疹疫苗接种纳入计划免疫管理提供科学依据，１９９６年以珠海市为试点，在该市三个区选择９４４名１～３０岁健康人群，用微量血球凝集抑制（ＨＩ）试验检测风疹ＨＩ抗体，总阳性率为６８．２％，几何平均滴度倒数（ＧＭＲＴ）为３６．１，其中＜１６岁儿童的风疹抗体阳性率和ＧＭＲＴ均明显低于≥１６岁人群。从９４４人中随机抽取１６９人接种风疹疫苗，观察免疫后的血清效果，免疫成功率为４７．３％，其中免前抗体阴性者，免后阳转率为９６．５％，免前抗体≤１：６４者，免疫成功率为９５．６％，免后比免前ＧＭ－ＲＴ增长９．３倍。同时对珠海市１～７岁儿童普遍接种风疹功苗，接种率为６１．２％，其中１岁儿童接种率７１．１％。疫苗接后未发现严重副反应，显示风疹疫苗有良好的免疫原性，安全可靠，建议逐步将风疹疫苗接种纳入计划免疫管理。
In order to provide a scientific basis for our province to include rubella vaccination into planned immunization management, Zhuhai was selected as a pilot in 1996 and 944 healthy people aged from 1 to 30 were selected in the three districts of the city for detection by the micro-hemagglutination inhibition (HI) test The total positive rate of Rubella HI antibody was 68.2% and the geometric mean reciprocal titer (GMRT) was 36.1. The positive rate of rubella antibody and GMRT in children <16 years old were significantly lower than those of children aged> 16 years old. 169 randomly selected from 944 people were vaccinated with rubella and the serum effect after immunization was observed. The success rate of immunization was 47.3%, in which the positive rate of immunization was 96.5% 1:64, the success rate of immunization was 95.6%, after the free pre-GM-RT increased by 9.3 times. At the same time, 1 ~ 7-year-old children in Zhuhai were vaccinated with rubella Gong Miao, the inoculation rate was 61.2%, of which 1-year-old children vaccination rate was 71.1%. Vaccination and found no serious side effects, showing that the rubella vaccine has good immunogenicity, safe and reliable, it is recommended that rubella vaccine should be gradually included in the planned immunization management.