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氟奋乃静癸酸酯注射液临床上用于治疗急、慢性精神分裂症。但其性质不稳定,特别在遇光线后,颜色很快由淡黄变黄、棕黄,最后变为棕红色。现已发现本品(不论是淡黄或深黄色)经贮藏后,其分解产物随时间的延长而增加,英国药典1975年增订本对该品用薄层层析法作“有关物质”检查。我国地方药品标准也规定对本品作“有关物质”检查。我们在使用本品过程中也发现该药含量与临床疗效都随着贮藏
Fluphenazine decanoate injection is clinically used to treat acute and chronic schizophrenia. But its nature is not stable, especially in case of light, the color quickly from yellow to yellow, brown, and finally into a reddish brown. It has been found that the product (whether yellow or dark yellow) after storage, its decomposition products increased over time, the British Pharmacopoeia 1975 an updated version of the product by thin-layer chromatography for “related substances” an examination. China’s local drug standards also provides for the goods for “related substances ” inspection. We use this product also found during the course of the drug content and clinical efficacy with the storage