采用脑立体定向手术治疗慢性精神分裂症。术后对３８例病人随访５～１０年，近期临床疗效及量表评定有效率分别为７６．３％与７８．５％，远期有效率分别为５０％与５７．１％。其中淡漠、退缩、思维障碍无显著改善；激活性高、敌对猜疑改善较为明显。８例韦氏智力测验、临床记忆量表测验的病人脑功能与术前持平。 Stereotactic surgery for chronic schizophrenia. Thirty-eight patients were followed up for 5 to 10 years. The effective rates of clinical efficacy and scale assessment were 76.3% and 78.5% respectively, and the long-term effective rates were 50% and 57.1% respectively. Among them, indifference, withdrawal, and thinking disorder did not significantly improve; the activism was high, and the hostility and suspicion improved more obviously. Eight cases of Wechsler intelligence test, clinical memory scale test of patients with brain function and preoperative flat.