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应用甲醛诱导促生长激素神经肽 (ｇａｌａｎｉｎ)基因敲除型 (ｇａｌ- /- )和野生型 (ｇａｌ+ /+ )小鼠的持续性伤害感觉模型 ,发现 ｇａｌ- /- 小鼠的反应性明显低 ,在第二反应阶段尤为明显。单侧后爪足底表面注射角叉菜胶的炎症性热痛觉过敏研究发现 ,ｇａｌ- /- 小鼠的热痛
Formaldehyde-induced sustained injury sensory model was induced in galanin gene knockout (gal- / -) and wild type (gal + / +) mice and found that the reactivity of gal- / - mice was significant Low, especially in the second reaction stage. Inflammatory thermo-hyperalgesia of carrageenan injected into the unilateral hind paw plantar surface found that heat pain in gal- / - mice