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[目的]观察光照治疗轻度抑郁症的临床疗效和不良反应。[方法]选取本院2010年1月2011年3月就诊的59例轻度抑郁症患者，随机分为观察组（30名）和对照组（29名），观察组采用强度为10000 Lux的光照治疗，对照组采用强度为100 Lux 的光照治疗，疗程均为6周。采用汉密尔顿抑郁量表（HAMD）和副作用量表（TESS）评定疗效及不良反应。[结果]观察组与对照组对比分析，HAMD 量表评定均有明显改善，差异有统计学意义（P ＜0．01），两组不良反应均很轻微。[结论]光照治疗对于轻度抑郁症安全有效。“,”[Objective]To observe the clinical efficacy and adverse reaction of light therapy for the treat-ment of mild depression.[Methods]A total of 59 patients with mild depression in our hospital from Jan.2010 to March 2011 were chosen and randomly divided them into observation group(n =30)and control group(n=29).The observation group was treated with 10000 Lux light therapy,while control group was treated with 100 Lux light therapy.Each group was treated 30 minutes every day.The treatment duration was 6 weeks. Hamilton rating scale for depression(HAMD)and side effect scale(TESS)were used to assess the efficacy and adverse reaction.[Results]Compared with control group,HAMD scores in observation group were obviously improved,and there was significant difference(P < 0.01).Adverse reactions of two groups were rare and mild.[Conclusion]Light therapy for the treatment of mild depression is safe and effective.