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非柯兴、非肢端肥大男性垂体嫌色细胞瘤起病隐袭,临床确诊时患者之垂体功能损害多已不可逆,故寻求早期诊断的线索实属必要。我院1958～1984年间共诊治该瘤患者70例。本文分析其临床表现、蝶鞍体积与内分泌功能改变的关系,结果表明:(1)本病确诊时多属晚期,视功能受损率高达75.7％,至少一只眼失明者占总例数之半。(2)性功能低减为首发症状者占42.1％,总发生率达69.9％。(3)蝶鞍体积小于2500mm~3组肾上腺皮质功能低减率显著低于体积大于2500mm~3组(发生率分别为17.6％及61.1％,P<0.01)。(4)测hGH储备功能者8例,明确为储备功
Non-Cochin, non-acromegaly men with pituitary chromophobe tumor insidious onset, the clinical diagnosis of patients with pituitary dysfunction has been irreversible, it is necessary to seek early diagnosis clues. Our hospital from 1958 to 1984, a total of 70 cases of patients with the tumor. This article analyzes the clinical manifestations, sella volume and changes in endocrine function, the results showed that: (1) the diagnosis of the disease are mostly late, as high as 75.7% impaired visual function, at least one blind eye, the total number of cases half. (2) 42.1% of the patients with low sexual function reduced to the first symptom, the total incidence was 69.9%. (3) The decreasing rate of adrenocortical function in the sella of less than 2500 mm ~ 3 was significantly lower than that in the group of 2500 mm ~ 3 (incidence 17.6% and 61.1%, P <0.01 respectively). (4) 8 cases of hGH reserve function, clear as reserve function