结扎蒙古沙土鼠颈总动脉,造成脑缺血模型,松解后,观察存活期14天、21天、28天的实验动物的大脑形态学和代谢功能的改变。结果显示大脑皮质、尾状核、海马和豆状核壳等部位对缺血损害最为敏感。存活4天～21天的动物对2-DG的摄取明显回升并缓慢恢复,血流恢复后28天的脑组织,其神经元结构出现不同阶段的恢复。 After the carotid artery of Mongolian gerbils was ligated and the model of cerebral ischemia was induced, the morphological and metabolic changes of brain in experimental animals at 14, 21 and 28 days of survival were observed. The results showed that cerebral cortex, caudate nucleus, hippocampus and lentiform nucleus were most sensitive to ischemic damage. After 4 days to 21 days of survival, the uptake and uptake of 2-DG obviously recovered and recovered slowly. After 28 days of blood flow recovery, the neuronal structure recovered in different stages.