佐剂应用于临床已有90多年的历史,它的研究和应用取得了巨大的进展。自从20世纪80年代纳米技术首次应用于疫苗佐剂以来,纳米技术在医学上的应用受到越来越多的重视,新的纳米佐剂不断面世,在疫苗等研究领域发挥了重要作用。本文就目前正在研究使用的无机纳米佐剂和有机纳米佐剂作一简要综述。 Adjuvants have been used clinically for over 90 years and great progress has been made in their research and application. Since the application of nanotechnology to vaccine adjuvants for the first time in the 1980s, more and more attention has been paid to the application of nanotechnology in medicine. New nanoe adjuvants have been introduced continuously and have played an important role in the field of vaccine research. This article is currently being studied using inorganic nano-adjuvants and organic nano adjuvants for a brief review.