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本文以针剂盐酸丁丙诺啡（ＢＵＰ）肌肉注射８—１０ｄ递减疗法对海洛因依赖者６３１例进行戒毒治疗，戒毒成功率为８７．６４％，脱试率为１２．３６％，通过临床治疗结果，并对其临床疗效进行评价。结果表明ＢＵＰ用于海洛因依赖的戒断治疗，选择合理递减疗程控制症状彻底，减药时戒断症状轻微平稳，治疗过程无明显兴奋及欣快表现，住院过程无强烈觅药行为，停药后戒断症状反应反复较少且不良反应轻微。本组治疗结果亦表明ＢＵＰ依赖性潜力低，成瘾性小，治疗过程无ＢＵＰ新的依赖性形成。绝大多数患者在住院期间情绪稳定，无行为偏倚，渴求淡漠，有利于心瘾的消除。治疗实践说明ＢＵＰ是一种比较好的海洛因依赖治疗药物，值得进一步推广应用。
In this paper, intraperitoneal injection of buprenorphine hydrochloride (BUP) intramuscular 8-10d descending therapy for 631 cases of heroin addicts was treated, the success rate of detoxification was 87.64%, the test-out rate was 12.36%, through the clinical treatment results , And evaluate its clinical efficacy. The results showed that BUP was used to heroin addicts in treatment of abstinence. The symptoms were controlled by decreasing the duration of heroin addicts. The abstinence symptoms were relieved mildly and smoothly during treatment. There was no obvious excitement and euphoria during the treatment. Withdrawal symptoms repeated less adverse reactions and mild. The results of this group also showed that BUP-dependent low potential, addiction is small, the process of treatment without the formation of new BUP dependencies. The vast majority of patients with stable mood during hospitalization, non-behavioral bias, desire indifference, is conducive to the elimination of heart addiction. Treatment practice shows that BUP is a good drug for heroin dependence and is worth further promotion.