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本文用组织胺吸入试验测定了33例缓解期哮喘患者、40例哮喘患儿双亲及3量侧正常儿童双亲的气道反应性。结果,哮喘组气道反应性最高,PC_(20)均小于3mg/ml,平均为0.59mg/ml(0.125～2.6mg/ml),对照组最低,PC_(20)均大于32mg/ml,而哮喘患儿双亲组介于两者之间,平均为11.6mg/ml(0.71～32mg/ml)。另外,过敏性鼻炎及荨麻疹患者的气道反应性也显著高于正常人,平均PC_(20)分别为3.1mg/ml和14.3mg/ml。以上结果提示哮喘患者家族成员可能是哮喘的易患人群。
In this paper, histamine inhalation test was used to determine the airway responsiveness in 33 remission asthmatic children, 40 asthmatic children with both parents and 3 normal children. The results showed that the highest level of airway reactivity was found in the asthmatic group, the PC_ (20) were less than 3mg / ml and the average was 0.59mg / ml (0.125 ~ 2.6mg / ml) Parents of children with asthma range between the two, with an average of 11.6mg / ml (0.71 ~ 32mg / ml). In addition, airway responsiveness in patients with allergic rhinitis and urticaria was also significantly higher than that in normal subjects, with mean PC 20 (20) of 3.1 mg / ml and 14.3 mg / ml, respectively. These results suggest that family members of asthmatics may be susceptible to asthma.