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当粪便蓄积在溃疡性结肠炎活动性病变区域以上的非炎性肠管时,就可能发生近段粪便的壅滞,其机制尚不清楚。本文结果证实大约10%的远段结肠炎病人合并有粪便壅滞。方法:经乙状结肠镜检查并直肠活检确诊的52例活动性溃疡性直肠结肠炎病人进入这组研究。每例病人每晚服含有10个志物的胶囊(硫酸钡浸透的聚乙烯小丸,平均重量为27mg)一枚,共14天,于第15天下午2点摄腹部平片,测定存留标志物数目,以此来估计结肠转运时间。根据22例健康人检测结果,90%滞留3~61标志物,故肠近段粪便壅滞的含意是指患者存留70个或更多的标志物。
When faeces accumulate in the non-inflammatory bowel region above the active lesion area of ulcerative colitis, there is a possibility that stool lag may occur in near range, and the mechanism thereof is unclear. Our results confirm that about 10% of patients with distal colitis have stool stagnation. METHODS: Fifty-two patients with active ulcerative colitis confirmed by sigmoidoscopy and rectal biopsy were enrolled in this study. Each patient served 10 capsules per capsule (barium sulphate soaked polyethylene pellets with an average weight of 27 mg) a day for 14 days and was taken at 2 pm on the 15th day to determine the remaining markers In order to estimate colon transit time. According to 22 healthy people test results, 90% retained 3 to 61 markers, so the meaning of intestinal stool stagnation refers to the retention of 70 patients or more markers.