糖尿病(DM)是一种多器官、多组织受累的代谢性疾病。其勃起功能障碍的发病率可达35%~50%,病程超过5年的患者可高达75%[1],但其发病机制并不完全清楚。同时,临床研究表明,DM不仅可以影响勃起功能,还可以涉及到射精和生殖系统,引起逆行射精和男性不育[1]。附睾是精子运输、储存和 Diabetes mellitus (DM) is a metabolic disease in which multiple organs and tissues are involved. The incidence of erectile dysfunction can reach 35% to 50%, and the duration of patients with more than 5 years of disease can reach as high as 75% [1], but the pathogenesis is not completely clear. At the same time, clinical studies have shown that DM can not only affect erectile function, but also involve ejaculation and the reproductive system, causing retrograde ejaculation and male infertility [1]. The epididymis is sperm transport, storage and