目的:观察克林霉素治疗肺部感染的临床疗效及不良反应。方法:60例确诊为肺部感染的住院患者给予克林霉素磷酸酯0.9g加入生理盐水250ml中静脉滴注,每日2次,连续7～14日。结果:克林霉素治疗肺部感染的总有效率为76.7％,细菌清除率为73.2％。不良反应发生率为5％。结论:克林霉素可作为治疗金黄色葡萄球菌、肺炎链球菌和溶血性链球菌等需氧革兰阳性菌引起肺部感染的良好抗菌药物。 Objective: To observe the clinical effects and adverse reactions of clindamycin in the treatment of pulmonary infection. Methods: Sixty hospitalized patients diagnosed as pulmonary infection were given clindamycin phosphate 0.9g by adding 250ml normal saline intravenously, twice daily for 7 ~ 14 days. Results: The total effective rate of clindamycin in treating pulmonary infection was 76.7% and the bacterial clearance rate was 73.2%. The incidence of adverse reactions was 5%. Conclusion: Clindamycin can be used as a good antimicrobial agent for pulmonary infections caused by aerobic gram-positive bacteria such as Staphylococcus aureus, Streptococcus pneumoniae and Streptococcus hemolyticus.