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目的通过检测从业人员血液中戊型肝炎病毒IgM(HEV-IgM)抗体,了解戊型肝炎(以下简称戊肝)在正常人群中的隐性感染情况,为预防和控制戊肝的流行提供依据。方法对2011年到天津市和平区疾病预防控制中心进行健康检查的天津市从业人员共33 211人的HEV-IgM抗体进行检测,并对检验结果进行分析。结果 2011年天津市从业人员33 211人中HEV-IgM抗体阳性为22人,阳性率为0.66‰;高于临床报病发病率的47.8倍。在检测人群中以31~40岁年龄组HEV-IgM抗体检出比例最高,被检出人员均无肝炎相关症状和其他阳性体征;经χ2检验,不同性别、不同职业的HEV-IgM抗体阳性率差异无统计学意义。结论加强对从事服务领域的人员隐形感染的筛查,对保护人群具有十分重要的意义。
Objective To detect HEV-IgM antibodies in the blood of practitioners so as to understand the latent infection of hepatitis E (HEV) in the general population and provide a basis for preventing and controlling the prevalence of HEV. Methods A total of 33 211 HEV-IgM antibodies from Tianjin practitioners who were in Tianjin Heping District CDC for medical examination in 2011 were tested, and the test results were analyzed. Results In 2011, the number of HEV-IgM antibodies in 33 211 people in Tianjin was 22, with a positive rate of 0.66 ‰, which was 47.8 times higher than the incidence of clinical reports. The detection rate of HEV-IgM antibody was the highest in 31-40 age group in the detection population. No hepatitis-related symptoms and other positive signs were found in the detected population. The positive rate of HEV-IgM antibody in different sexes and occupational groups by χ2 test The difference was not statistically significant. Conclusion Enhancing screening of invisible infection among service personnel is of great significance to the protection of the population.