It is widely accepted that hydrogeochemistry of saline springs is extremely important to understand the water circulation and evolution of saline basins and to evaluate the potential of potassium-rich evaporites. The Kuqa Basin, located in the north part of the Tarim Basin in Northwest China, is a saline basin regarded as the most potential potash-seeking area. However, the origin and water circulation processes of saline springs have yet to be fully characterized in this saline basin. In this study, a total of 30 saline spring samples and 11 river water samples were collected from the Qiulitage Structural Belt (QSB) of the Kuqa Basin. They were analyzed for major (K+, Ca2+, Na+, Mg2+, SO42?, Cl? and HCO3?) and trace (Sr2+ and Br?) ion concentrations, stable H-O-Sr isotopes and tritium concentrations in combination with previously published hydrogeochemical and isotopic (H-O) data in the same area. It is found that the water chemical type of saline springs in the study area belonged to the Na-Cl type, and that of river water belonged to the Ca-Mg-HCO3-SO4 type. The total dissolved solid (TDS) of saline springs in the QSB ranged from 117.77 to 314.92 g/L, reaching the brine level. On the basis of the general chemical compositions and the characteristics of the stable H-O-Sr isotopes of saline springs, we infer that those saline springs mainly originated from precipitation following river water recharging. In addition, we found that saline springs were not formed by evapo-concentration because it is unlikely that the high chloride concentration of saline springs resulted in evapo-concentration and high salinity. Therefore, we conclude that saline spring water may have experienced intense evapo-concentration before dissolving the salty minerals or after reting to the surface. The results show that the origin of salinity was mainly dominated by dissolving salty minerals due to the river water and/or precipitation that passed through the halite-rich stratum. Moreover, there are two possible origins of saline springs in the QSB: one is the infiltration of the meteoric water (river water), which then circulates deep into the earth, wherein it dissolves salty minerals, travels along the fault and rets to the surface; another is the mixture of formation water, or the mixture of seawater or marine evaporate sources and its subsequent discharge to the surface under fault conditions. Our findings provide new insight into the possible saltwater circulation and evolution of saline basins in the Tarim Basin.