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甲氰咪胍于1977年用于临床,化学结构与甲硫咪胺近似,亦有发生骨髓抑制的可能。文献已有甲氰咪胍引起白细胞减少的报道,引起单纯血小板减少者少见。作者报告1例女性65岁,因结肠腺癌复发住院。术后为防止应激性溃疡应用了甲氰眯胍(300 mgI.V.Q 6 h)。患者入院时血小板计数276,000,用药前273,000,用药后2天血小板降至35,000,停药后8天血小扳回升至164,000。1个月后由于胃瘘管内出
Cimetidine used in clinical trials in 1977, the chemical structure and methimazine approximation, but also the possibility of occurrence of bone marrow suppression. Cimetidine has been reported in the literature of leukopenia caused by rare thrombocytopenia caused by rare. The authors report a female 65 years old, hospitalized for recurrent colon adenocarcinoma. Postoperative application of metformin to prevent stress ulcer (300 mgI.V.Q 6 h). The patient’s platelet count was 276,000 at admission, 273,000 before medication, and the platelet count was reduced to 35,000 two days after drug withdrawal. After 8 days of withdrawal, the platelet count rose back to 164,000.1 months.