1910年Meige描述一种特发性眼睑痉挛和口下颌张力障碍综合征。女性较男性为多,常发生于30～70岁,其特征是双眼睑痉挛和口腔周围、额、颈肌肉不自主运动,极少影响其它肌群,典型特征为累及眼轮匝肌。开始为眨眼次数增多,继而出现不可控制的强直性眼脸痉挛,影响视力,可持续几秒到几分。在仰视或紧张时可诱发,入睡和稍主动控制即能消失,似乎不可能是周围神经损害所致,本文报导3例Meige综合征,1例为特发性的,另2例则由抗精神病药引起。例1,女性,45岁,已婚。病前体健,无任何精神障碍。数年前在全麻下作不大的腹部手术后很快自觉眼睑痉挛,术后一个月觉眨眼次数增多,未加注意,逐渐出现眼肌 1910 Meige describes an idiopathic blepharospasm and oral mandibular dystonia syndrome. More women than men, often occurs in 30 to 70 years old, characterized by double blepharospasm and around the mouth, forehead and neck muscles involuntary movements, minimally affect other muscles, the typical feature is involved orbicularis oculi muscle. The beginning of the blink of an eye increased, followed by uncontrolled tetanic eye cramps, affecting vision, sustainable a few seconds to a few minutes. In looking up or nervous can be induced to fall asleep and a little active control that can disappear, it seems unlikely that the peripheral nerve damage caused by this article reported 3 cases of Meige syndrome, 1 case of idiopathic and the other 2 cases by the antipsychotic Drug caused. Example 1, female, 45 years old, married. Pre-sick health, without any mental disorders. A few years ago under general anesthesia for minor abdominal surgery after conscious blepharospasm, a month after surgery blinks increased, without notice, the gradual emergence of oculomotor