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目的:了解四川省西昌市静脉吸毒人群丙型肝炎病毒(HCV)感染情况及其影响因素。方法:于2005年10月至11月在西昌市对静脉吸毒人群进行问卷调查,调查内容包括社会人口学、毒品使用、共用注射器具静脉吸毒以及性行为情况等,同时采集血样进行HCV抗体检测。结果:在招募的325名静脉吸毒者中,HCV感染率为61.8%(201/325)。多因素Logistic回归模型分析结果显示,无业(OR,1.90;95%CI,1.11-3.24)、近3个月共用针头或注射器(OR,2.40;95%CI,1.16-4.99)以及近6个月以性交为条件接受性伴提供的钱物、毒品或住处(OR,8.96;95%CI,1.15-69.58)与静脉吸毒人群HCV感染的关系有统计学意义。结论:四川省西昌市静脉吸毒人群中HCV感染率仍在升高,应该在该地区进一步加大干预工作的力度以控制HCV的传播。
Objective: To understand the prevalence of hepatitis C virus (HCV) in intravenous drug users in Xichang, Sichuan Province and its influencing factors. Methods: A questionnaire survey of intravenous drug addicts in Xichang City from October to November in 2005 was conducted. The survey included social demography, drug use, intravenous drug use in shared syringes and sexual behaviors. Meanwhile, blood samples were collected for HCV antibody testing. Results: Of the 325 intravenous drug users recruited, the HCV infection rate was 61.8% (201/325). Multivariate Logistic regression model analysis showed that the unemployed (OR, 1.90; 95% CI, 1.11-3.24) shared needle or syringe (OR, 2.40; 95% CI, 1.16-4.99) in the last 3 months and nearly 6 months Drugs or dwellings (OR, 8.96; 95% CI, 1.15-69.58) were associated with HCV infection in intravenous drug users as a result of sexual intercourse. CONCLUSIONS: The prevalence of HCV infection among intravenous drug users in Xichang, Sichuan province is still rising. Intervention efforts should be further stepped up in this area to control the spread of HCV.