论文部分内容阅读
睾丸癌的流行病学研究表明母体妊娠时,用过外源性雌激素及内源性雌激素水平升高均可增加子代患此病的危险孕前体重过重及妊娠时恶心严重者,也可增加危险性。近年来 McMahon 等发现吸烟是一种影响雌激素水平的因素,这可能是吸烟对卵巢的直接作用所致,而 Michnovicz 等认为吸烟可明显影响 E_2的降解过程,特别是吸烟者 E_2的2-羟化作用明显增强。本文研究了吸烟对孕妇血中 hCG、E_2水平的影响,研究包括1958～1965年间美国的12所大学附属医疗中心147例孕妇,大多数为初孕妇,分四组:A 组33例,B 组34例,C 组36例,D 组44例,年龄分别为22.6±3.2岁,23.0±3.8岁,22.7±3.3岁和25.7岁±5.2岁,孕前体重分别为56.9±7.9kg,55.7±8.0kg,52.7±7.4kg,58.3±11.4kg,孕
Epidemiological studies of testicular cancer show that maternal pregnancy, exogenous estrogen and endogenous estrogen levels increased can increase the risk of offspring with pre-pregnancy weight and severe nausea during pregnancy also Can increase the risk. In recent years, McMahon et al found that smoking is a factor that affects the estrogen level, which may be caused by the direct effect of smoking on the ovary. However, Michnovicz et al think smoking can significantly affect the degradation process of E 2, especially the 2-hydroxy The role of significantly enhanced. This study investigated the effect of smoking on hCG and E_2 levels in pregnant women. The study included 147 pregnant women at the affiliated medical centers of 12 universities in the United States from 1958 to 1965, most of them pregnant women, divided into four groups: group A 33 cases, group B 34 cases, 36 cases in group C and 44 cases in group D, with the average age of 22.6 ± 3.2 years, 23.0 ± 3.8 years, 22.7 ± 3.3 years and 25.7 years ± 5.2 years. The pre-pregnancy weights were 56.9 ± 7.9kg and 55.7 ± 8.0kg , 52.7 ± 7.4 kg, 58.3 ± 11.4 kg, pregnant