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药物治疗急性心肌梗塞(心梗)后左室功能哀竭的目的在改善心室功能、气体交换、全身氧输送和保证心肌氧合。深入理解心室衰竭时的压力—容积关系紊乱是正确治疗的基础。急性心梗后的压力—容积关系正常心动周期的左室压力—容积关系为:舒张期间,随左室充盈,扩张性降低,呈曲线性关系;收缩期间,左室射出血液,直至收缩末容积,后者的大小取决于心肌收缩力和后负荷。后负荷愈高,收缩末容积愈大,二者呈直线关系,其斜率反映心室收缩力。
Medical treatment of acute myocardial infarction (MI) after the purpose of left ventricular dysfunction in improving ventricular function, gas exchange, systemic oxygen delivery and to ensure myocardial oxygenation. In-depth understanding of the pressure-volume relationship during ventricular failure is the basis for proper treatment. Pressure-Volume Relationship After Acute Myocardial Infarction The left ventricular pressure-volume relationship during normal cardiac cycle is: during diastole, with left ventricular filling, dilatation decreased, showing a curvilinear relationship; during systole, the left ventricle exuded blood until the end-systolic volume , The size of the latter depends on myocardial contractility and afterload. After the higher load, the greater the volume of the end of systole, the two showed a linear relationship, the slope reflects the ventricular contractility.