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凝血貭(thromboplastinum)为自新鮮酵母、牛脑或其他动植物組織中提出的一种磷脂类化合物,已收載于1959年版中国药学会上海分会編的《药品規范》中。其制剂的合理使用在于使出血局部施药时能发揮加速血凝作用,要求效果愈高愈好,因而关于它的生物检定是属于限度試驗性貭。用去鈣血浆測凝法的試驗,是比較簡便的方法。上海市1956年版《药品規范》卽采用此法,但几年来国內各地試驗結果,表明存在很多問題,实驗結果的差异很大。1951年《美国新药和非法定药集》規定用本法时在对照管20-30分钟不
Thromboplastinum is a phospholipid derived from fresh yeast, bovine brain or other animal and plant tissues and was included in the 1959 Code of Practice of the Shanghai Branch of the Chinese Pharmaceutical Association. The rational use of its preparation is that hemorrhagic local application can accelerate the role of blood coagulation, the higher the effect required the better, and therefore its biological test is a limit test 貭. With the method of coagulation coagulation test, is a relatively simple method. Shanghai 1956 version of the “drug norms” 卽 adoption of this method, but over the years test results across the country, indicating that there are many problems, the experimental results vary widely. 1951 “New Drugs and Non-Statutory Drugs in the United States” stipulates that this method should be used in control tubes for 20-30 minutes