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奥美拉唑(Omeprazole)是胃壁细胞膜的质子泵阻滞剂,能有效地抑制胃酸分泌,对各种原因引起的胃酸分泌增加所致消化道溃疡并发的上消化道出血疗效明显优于西咪替丁。我院于1990～1995年应用奥美拉唑注射液治疗高血压脑出血并发的上消化道出血51例,并与西咪替丁注射液进行比较,结果如下。 1 资料与方法 1.1 病例选择及分组:全部126病例均系头颅CT或MRI诊断为高血压脑出血,并通过抽取胃液化验及便潜血确认存在上消化道出直的患者,既往有高血压史,其中基底节区、桥脑及丘脑血肿124例,小脑半
Omeprazole is a proton pump inhibitor of the parietal cell membrane, which can effectively inhibit the secretion of gastric acid. The curative effect of upper gastrointestinal bleeding caused by peptic ulcer accompanied by increased gastric acid secretion caused by various causes is obviously better than that of cimetidine For Ding. Our hospital from 1990 to 1995 with omeprazole injection of hypertensive intracerebral hemorrhage complicated by upper gastrointestinal bleeding in 51 cases, and compared with cimetidine injection, the results are as follows. 1 Materials and Methods 1.1 Case Selection and Grouping: All 126 cases were diagnosed by head CT or MRI of hypertensive intracerebral hemorrhage, and by gastric juice sampling and occult blood confirmed the presence of upper gastrointestinal tract in patients with previous history of hypertension, Including basal ganglia, pons and thalamus hematoma in 124 cases, cerebellar half