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丁胺卡那霉素(Amikacin)为白色或类白色结晶性粉末,熔点230～240℃,无臭,无味,在水中易溶,在乙醇中不溶。丁胺卡那霉素是在卡那霉素分子的去氧链霉胺分子部分的C_1氨基上接上[L-(-)-4-氨基-2-羟基丁酰]侧链而得的新氨基糖甙类抗生素。对革兰氏阴性杆菌和葡萄球菌具有杀菌作用。不仅对卡那霉素、庆大霉素敏感菌有效。对氨基糖甙类抗生素耐药的绿脓杆菌、大肠杆菌、变形杆菌、克雷伯氏菌属都有明显的作用,对耐药的葡萄球菌亦有效、与它剂之间几
Amikacin is a white or almost white crystalline powder with a melting point of 230-240 ℃. It is odorless, tasteless, soluble in water and insoluble in ethanol. Amikacin is a newly added [L - (-) - 4-amino-2-hydroxybutyryl] side chain attached to the C 1 amino group of the molecule of deoxystreptamine of kanamycin Aminoglycoside antibiotics. Gram-negative bacilli and staphylococcus have bactericidal effect. Not only kanamycin, gentamicin-sensitive bacteria effective. Pseudomonas aeruginosa resistant to aminoglycoside antibiotics, Escherichia coli, Proteus, Klebsiella has a significant role in the resistance of Staphylococcus aureus is also effective, and its agents between the few