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观察27例尿毒症患者醋酸盐血液透析前后血液流变学的变化。结果显示:尿毒症患者血液透析后,全血表观粘度、红细胞压积、红细胞刚性、红细胞变形指数、红细胞聚集指数均增大(P<0.05);血浆粘度、纤维蛋白原变化无显著性(P>0.05)。提示尿毒症患者血液透析后血液粘度增大,可能主要在于红细胞硬度增加,而血浆粘度无改变。
The changes of hemorheology in 27 patients with uremia before and after acetate hemodialysis were observed. The results showed that after hemodialysis, the apparent viscosity, hematocrit, erythrocyte rigidity, erythrocyte deformability index and erythrocyte aggregation index increased in hemodialysis patients (P <0.05). There was no significant change in plasma viscosity and fibrinogen (P> 0.05). Prompted uremic patients after hemodialysis increased blood viscosity, may be mainly due to an increase in red blood cell hardness, while no change in plasma viscosity.