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本文分析62例小儿临床诊断为葡萄球菌败血症病例,其中血或(和)骨髓培养为金黄色葡萄球菌株者26例,培养出表皮葡萄球菌株者13例,培养阴性23例,三组均存在原发感染灶、有高热、白细胞总数高或低下等中毒症状和体征,迁徙性并发症发生率为73％,病死率为16.1％,金葡菌组和培养阴性组在并发症发生率和治疗无效率上基本相同;表葡菌组凝固酶阳性率和并发症发生率均明显低于金葡菌组。全组结核菌素试验者13例,12例阴性,提示本病存在细胞免疫功能低下。治疗体会认为以三种抗生素联合静脉用药,剂量足、疗程要长。迁延病例除变换抗生素外,还要适当使用新鲜血或血浆,进一步加强支持治疗。
In this paper, 62 cases of pediatric clinical diagnosis of staphylococcal sepsis cases, including blood or (and) bone marrow culture Staphylococcus aureus were 26 cases, Staphylococcus epidermidis strains were cultured in 13 cases, culture negative in 23 cases, three groups were present Primary infection, high fever, high or low total leukocyte count and other symptoms and signs of poisoning, the incidence of migratory complications was 73%, the mortality rate was 16.1%, Staphylococcus aureus and culture negative group in the incidence and treatment of complications The efficiency is basically the same; coagulase group of Staphylococcus aureus positive rate and complication rate were significantly lower than Staphylococcus aureus group. The whole group of tuberculin test in 13 cases, 12 cases were negative, suggesting that there is cellular immunity in this disease is low. Treatment experience that three antibiotics combined with intravenous medication, enough dosage, long course of treatment. In addition to converting patients to delay the transformation of antibiotics, but also the appropriate use of fresh blood or plasma, to further strengthen the supportive treatment.