论文部分内容阅读
目的 评价晚期食管癌支架置入术后放疗和 (或 )化疗的价值。方法 通过对 5 3例晚期食管癌患者前瞻性随机对照研究 ,比较单纯支架置入术组与支架置入术后放疗和 (或 )化疗组的总生存期、生活质量 (KPS)评分及并发症发生率。结果 单纯支架置入术组与支架置入术后放疗和(或 )化疗组相比 ,治疗后的吞咽功能分级、KPS评分、并发症发生率差异无显著性 ;再狭窄发生率分别为 9/ 2 7和 1/ 2 6 ,差异有显著性 (P =0 .0 0 7) ,两组平均生存期分别为 (2 4 5± 4 1)d和 (2 6 2± 4 3)d ,差异无显著性 (P =0 .813)。结论 晚期食管癌支架置入术后续行的放疗和 (或 )化疗降低了再狭窄的发生率 ,未延长患者的生存期。
Objective To evaluate the value of radiotherapy and / or chemotherapy after advanced esophageal cancer stent implantation. Methods A prospective randomized controlled study on 53 patients with advanced esophageal cancer was performed to compare the overall survival, quality of life (KPS) scores and complications in radiotherapy and / or chemotherapy group after stent implantation alone or in combination with stent implantation Occurrence rate. Results Compared with the radiotherapy and / or chemotherapy group after stent implantation, there was no significant difference in the classification of the swallowing function, the KPS score and the complication rate after restenosis. The incidences of restenosis were 9 / The average survival time was (2 45 ± 4 1) days and (2 6 2 ± 4 3) days respectively in the two groups (P 0.707) No significant (P = .813). Conclusions The radiotherapy and / or chemotherapy after esophageal cancer stent implantation reduces the incidence of restenosis and does not prolong the survival of patients.